Monday, July 15, 2013

Bachmann nearly pays off presidential campaign debt, spends $175,000 on legal fees

WASHINGTON ? Michele Bachmann's presidential campaign?debt continues to dwindle, and the campaign has begun paying off its legal fees.?

Bachmann paid down more than $100,000 in outstanding debt during the second quarter after transferring $140,000 from her congressional campaign committee. She has $30,000 in debt remaining, most of which is owed to Florida firm Robert Watkins & Co., whose Nancy Watkins serves as the campaign?s treasurer.

New Bachmann for President expenses include nearly $49,000 for legal fees and services paid to D.C. law firm Patton Boggs. Her congressional campaign sent the firm an additional $120,000. The firm represents Bachmann and her presidential campaign and has helped her navigate both a now-settled civil suit in Iowa and investigations into the campaign?s spending habits by a handful of organizations, including the FBI and the Federal Elections Commission. The presidential campaign also paid the firm $6,248 for earlier obligations.

Bachmann?s congressional campaign raised $822,000 and has $1.8 million on hand. On May 29, Bachmann announced she will not run for re-election.

Look for our traditional quarterly fundraising round-up sometime Tuesday.

Devin Henry can be reached at dhenry@minnpost.com.

Source: http://feeds.minnpost.com/~r/minnpost/~3/fiZikOLb0OA/bachmann-nearly-pays-presidential-campaign-debt-spends-175000-legal-fees

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Most popular ovarian cancer cell lines do not resemble ovarian cancer

(Medical Xpress)?Researchers from Memorial Sloan-Kettering Cancer Center recently discovered that the most frequently used cancer cell lines in ovarian cancer research are not suitable models of ovarian cancer. Their findings are the result of a detailed review of genomic data that recently became publicly available. Their methods, published in this week's Nature Communications, could provide a usable framework for other researchers to better assess cell lines' validity for future use in this and in other types of cancer research.

Computational biologists Nikolaus Schultz and Rileen Sinha, and biochemist Silvia Domcke, focused their review on high-grade serous ovarian cancer (HGSOC), the most commonly diagnosed and frequently studied subtype of ovarian cancer. Using datasets from The Cancer Genome Atlas and the Cancer Cell Line Encyclopedia, which detail and define the genomic features of numerous clinical samples and cell lines, the team analyzed and then ranked several cell lines by their genomic similarities to tissue samples and, in doing so, uncovered multiple discrepencies between the cell lines and actual human tumors.

"Our review showed that the two most utilized cell lines, accounting for almost 60 percent of all published research studies, do not resemble HGSOC well at all," explained Dr. Schultz, the paper's lead author. "The problem with this is, investigators assumed they were studying high-grade serous ovarian cancer, when in reality they were looking at something else. So conclusions drawn from this work might be misleading."

Cancer cell lines are generated and grown indefinitely in laboratories around the world, but are ultimately derived from human tumors. For the past several decades, they have been the most popular model for the study of cancer because they are inexpensive and easy to replicate. However, the origin of some cell lines is not well established, and through years in culture, they can acquire additional changes, making them less desirable.

"With the explosion of genomic data now at our fingertips and the potential for more to become available, it's our hope that this approach can be used by our colleagues to choose optimal cell lines, as we do expect similar discrepencies in other tumor types," said Dr. Schultz. "Overall, we believe these findings should greatly benefit the study of cancer."

Source: http://medicalxpress.com/news/2013-07-popular-ovarian-cancer-cell-lines.html

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Sunday, July 14, 2013

Obama: Immigration overhaul can boost recovery

WASHINGTON (AP) ? President Barack Obama says overhauling the nation's immigration system can provide a big boost to the economic recovery.

In his weekly Internet and radio address, Obama cites former President George W. Bush's support for a comprehensive solution on immigration. He says if Democrats and Republicans can agree on something, it's a good place to start.

The Senate has already passed a bipartisan bill. Obama says now the House must act. He says Americans should use email and Facebook and phone calls to tell their representatives to take action.

In the Republican address, Sen. Mike Enzi of Wyoming says Americans are paying the price for Obama's health care law. He says it's time to admit the law is failing. He's urging a "permanent delay" in the law's implementation.

___

Online:

Obama address: www.whitehouse.gov

GOP address: www.youtube.com/gopweeklyaddress

Source: http://news.yahoo.com/obama-immigration-overhaul-boost-recovery-100430320.html

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U.S. Internet Providers Target Chinese Cyberspies

U.S. Internet Providers Target Chinese Cyberspies | www.wokv.com

The U.S. government gave American Internet providers addresses linked to suspected Chinese hackers earlier this year as part of a previously undisclosed effort aimed at blocking cyberspying. Danny Yadron reports on Lunch Break.

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Source: http://www.wokv.com/videos/news/us-internet-providers-target-chinese-cyberspies/v6Wpj/

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Saturday, July 13, 2013

In/Flux: What does the Microsoft shakeup mean?

Your embarrassing Facebook secrets now searchable

For months Facebook has been testing Graph Search, a function that itemizes user data into an easily searchable form. Search ?People in Seattle who like the Republican Party? and voila, over a hundred local contrarians pop up. Last Monday the company started rolling it out globally, and already people are getting creative with it.

For those who haven't yet gotten around to strengthening their Facebook security settings, this is a public service announcement: It?s time to get on that. To illustrate, we point out that several locals are public fans of Ashley Madison, a service that helps people cheat on their spouse. At press time, companies that hire Seattleites who like ?stealing? include Microsoft and GameStop. And for some professionals, publicly liking ?weed? or ?getting high? may not be a boon for their careers, recent ballot initiatives notwithstanding.

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There?s an expression that ?If you?re not paying for it, you?re the product.? With Facebook attempting to convince disappointed investors that the company?s hustling, they?ve been pulling out all the stops to organize their data in a way that?s useable to marketers, and moderately compelling to others. Users should be prepared for this sort of thing, not surprised.

Price-fixing? Who, Apple?

Even by the litigious standards of the tech world, it was a banner week for Apple and Amazon. And one that could yield cash for thousands of consumers.

Back in 2009, Apple decided to enter the e-book market, on which Amazon had a firm stranglehold. The problem was Amazon sold e-books at a loss in order to drive sales of the Kindle, something book publishers and Apple weren?t keen on. Flash forward a few months, and the e-book prices from nearly every major publisher spiked, coincidentally at the same time Apple launched their iBookstore.?

Last week a federal court ruled that Apple engaged in an illegal price fixing conspiracy with publishers, in a case brought against them by the federal government and 33 states. This verdict opens Amazon up to reassert itself as the 800 pound gorilla of the e-publishing world, discounting books at will and driving out competitors like Apple and Barnes & Noble.

What this could mean for local consumers is murkier. While Apple claims they will appeal the decision, they?re likely going to pay damages, and those who bought an e-book in the past few years are potentially looking at some compensation. Washington wasn?t one of the states participating in the case, but a private class action has already been filed to represent WA?s digital book buyers. According to Janelle Guthrie, spokeswoman for the WA Attorney General's office, ?Washington consumers will still benefit from this action.?

Seattle turns Big Data into energy savings

A lot of hype has been spun around ?Big Data,? a term vaguely referring to ? you guessed it ? analyzing vast troves of information. Touted as the key to the utopian social engineering of tomorrow (or at least better marketing), more examples appear of its potential every year. Last week Microsoft and partners moved to prove its worth further.

Microsoft, working with the City of Seattle and City Light, has launched a pilot named ?High Performance Buildings? project, aimed at using data to reduce energy consumption in Seattle?s commercial buildings. The project is a joint venture between Microsoft, management consulting firm Accenture and Seattle 2030, a collaborative group of downtown property owners out to slash Seattle?s energy consumption in half.

Brian Geller, Executive Director of Seattle 2030, tells Crosscut these savings will be created through the intensive analysis of building energy use, on such areas as heating and cooling systems, and will allow building managers to dictate where modifications and process changes are needed. According to Geller, if this system is adopted by enough additional buildings beyond the pilot, it ?could help us reach our collective 50 percent energy reduction goal well before 2030.?

Microsoft?s long-rumored ?reorganization? is underway.?On Thursday, CEO Steve Ballmer sent a public?memo?to employees, announcing a complete restructuring of the company. The transition is in its early stages, however, and beyond the who?s-in-who?s-out management shuffle and department streamlining, it?s tough to make heads or tails of it quite yet.

Ballmer claims the changes would help create ?One Microsoft.? That's in contrast to the current system, in which separate departments are known to be fiercely independent. Microsoft has been touting a more integrated company for years now, and reshuffles have become an?annual event. That said, this is one of their more significant shake-ups, streamlining its product buckets down to four areas: operating systems, apps, the cloud and devices. This could conceivably curb the infighting that has slowed the company's progress at times.

Furthermore, Ballmer has made some serious management changes. Some, such as putting Windows Phone OS lead Terry Myerson in charge of all operating systems and Bing chief Qi Lu in charge of apps, make sense. Others are less intuitive, such as making Julie Larson-Green ? a company veteran who?s focused on software before now ? the head of hardware engineering for the Surface, Xbox and other future devices.?

Proponents?are claiming?this could lead to a leaner, more collaborative Microsoft. On the other hand, this reorg assimilates some of their most successful projects ? such as Xbox and MS Office ? into the overall company, potentially leading to reduced flexibility in some areas. There are also?rumors?that lower performing products, such as the Bing search engine, could be left in the cold over time.

Could these changes create a better Microsoft? We welcome your opinions in comments.

Tech Bytes from Elsewhere

  • Where the Wild Things Are: WalkScore creates a ?heat map? of crime in Seattle. One takeaway: Ballard is surprisingly serene.
  • The Truth Hurts: Facebook announces that ?We will make our product worse, you will be upset, and then you will live with it.? Sure it?s an Onion parody, but let?s be real: at some point this has been said in Facebook HQ.
  • Go Go Gadget Prophesy: The1980s cartoon Inspector Gadget was spookily ahead of its time.
  • Minor Mind Melds: This summer?s best monster movie, Pacific Rim, features mammoth robots controlled by psychic-linked pilots. Could it happen? Kinda maybe!

Source: http://crosscut.com/2013/07/13/technology/115529/flux-msft-shakes-thing/

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